Scientific Reference
BPC-157
Evidence profile: Preclinical, with limited uncontrolled human reports
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids, derived from a naturally occurring protective protein found in human gastric juice. It has been extensively studied for its regenerative, cytoprotective, and anti-inflammatory properties across multiple tissue types. Research has focused on its ability to accelerate healing in tendons, ligaments, muscles, and gastrointestinal tissues. Its mechanisms involve modulation of angiogenesis, collagen synthesis, and growth factor signaling, making it a broadly acting repair peptide with both local and systemic effects.
Published Research
Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians
Mayfield CK et al. · The American journal of sports medicine · 2026 · Review
PMID 41476424 — View on PubMedFrom Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management
Yuan C et al. · International journal of molecular sciences · 2026 · Review
PMID 41898733 — View on PubMedEffect of BPC-157 on Symptoms in Patients with Interstitial Cystitis: A Pilot Study
Lee E et al. · Alternative therapies in health and medicine · 2024 · Clinical
PMID 39325560 — View on PubMedProtective effects of BPC 157 in rats with experimentally induced lower extremity ischemia-reperfusion injury
Yıldırım AK et al. · Scientific reports · 2026 · Preclinical
PMID 42204242 — View on PubMed